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Professional profile
My primary teaching responsibilities relate to the areas of
genetics and cell biology, offering courses for both the science major as well
as non-majors. By their nature,
biology courses can be ‘content heavy’ and while mastery of a body of
information is important, one of my goals is to impart a genuine interest in
the subject. This is done by
keeping the course content relevant and current in these rapidly advancing areas. I also feel that it is very important
to engage our students in collaborative research work in our laboratories. Students working in our labs gain a
deep understanding and appreciation of the field, and I find these experiences
to be very rewarding.
Work in my lab includes the study of polyamines, a group of
compounds derived from the amino acids ornithine and arginine. These
compounds are known to be important in several cellular functions including
cell division, response to stress and the development of most higher eukaryotes. The role of polyamines and their
related enzymes on cellular proliferation and metabolism has been the focus of
my lab for over 20 years.
Currently, students in my lab are characterizing the effect
of experimental compounds on the enzymes responsible for the biosynthesis (ODC
- ornithine decarboxylase) and degradation (SSAT - spermidine-spermine acetyl
transferase) of polyamines in cancer cell lines. The abilities of compounds such as resveratrol to affect
polyamine metabolism, cell viability and apoptosis of breast cancer and
melanoma cell lines are being studied.
Our work is being extended
to study the effects of other plant-derived compounds and extracts on cancer
cell lines. Past work investigated
changes in polyamine metabolism during the response of cells to abiotic stress,
specifically, the induction of arginine decarboxylase in osmotically stressed Arabidopsis cells and the signals
mediating this response.
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Russell P. Feirer
Associate Professor of Biology
Location: John Minahan Science Hall
Room: 321
Phone: (920) 403-3187
Fax: (920) 403-4033
Mailing address:
St. Norbert College
100 Grant Street
John Minahan Science Hall, 321
De Pere, WI 54115-2099
russ.feirer@snc.edu
Academic credentials:
B.S., University of Wisconsin-Eau Claire
M.S., Iowa State University
Ph.D., University of Wisconsin
Courses taught:
BIOL 120 General Biology I
BIOL 244 Genetics
BIOL 371 Cellular Physiology
BIOL 373 Molecular Biology
BIOL 353 Biotechnology in a Global Society
BIOL 489 Biology of the Cancer Cell
Publications:
Publications and Presentations
Recent Student Collaborations:
Student Collaborations
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